CLINICAL TRIALS AND OBSERVATIONS A case-control study to assess the risk of immune thrombocytopenia associated with vaccines

نویسندگان

  • Lamiae Grimaldi-Bensouda
  • Marc Michel
  • Elodie Aubrun
  • Pamela Leighton
  • Jean-Francois Viallard
  • Daniel Adoue
  • Nadine Magy-Bertrand
  • Guillaume Tisserand
  • Mehdi Khellaf
  • Jean-Marc Durand
  • Philippe Quittet
  • Olivier Fain
  • Bernard Bonnotte
  • Anne Sophie Morin
  • Nicolas Limal
  • Nathalie Costedoat-Chalumeau
  • Nathalie Morel
  • Brigitte Pan-Petesch
  • Olivier Decaux
  • Matthieu Mahevas
  • Michel Ruel
  • Karim Sacre
  • Francois Lefrere
  • Lucien Abenhaim
چکیده

Lamiae Grimaldi-Bensouda,1,2 Marc Michel,3 Elodie Aubrun,1 Pamela Leighton,4 Jean-Francois Viallard,5 Daniel Adoue,6 Nadine Magy-Bertrand,7 Guillaume Tisserand,7 Mehdi Khellaf,3 Jean-Marc Durand,8 Philippe Quittet,9 Olivier Fain,10 Bernard Bonnotte,11 Anne Sophie Morin,10 Nicolas Limal,3 Nathalie Costedoat-Chalumeau,12 Nathalie Morel,12 Brigitte Pan-Petesch,13 Olivier Decaux,14 Matthieu Mahevas,3 Michel Ruel,15 Karim Sacre,16 Francois Lefrere,17 Lucien Abenhaim,4,18 and Bertrand Godeau,3 for the PGRx Immune Thrombocytopenia Study Group

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Morbidity and mortality in adults with idiopathic thrombocytopenic purpura

To study outcomes of adults with idiopathic thrombocytopenic purpura (ITP), we performed a follow-up study in a cohort of 152 consecutive patients who were treated according to a well-defined algorithm. Longterm outcomes were determined relative to the response 2 years after diagnosis, because most (93%) patients who ultimately attained platelet counts above 30.0 3 109/L (30 000/mL) did so with...

متن کامل

Challenges to the Design of Clinical Trials for Live-Attenuated Tetravalent Dengue Vaccines

Viral vaccines do not always produce beneficial results. In the 1960s, formalin-inactivated measles and respiratory syncytial viral vaccines established immune responses in recipient children that rendered them susceptible to severe and fatal disease accompanying breakthrough measles or RSV infections [1–3]. It has been understood for some time that dengue vaccines could be subject to a similar...

متن کامل

Translational nanoparticle engineering for cancer vaccines

Conventional cancer treatments remain insufficient to treat many therapy-resistant tumors.1 Cancer vaccines attempt to overcome this resistance by activating the patient's immune system to eliminate tumor cells without the toxicity of systemic chemotherapy and radiation. Nanoparticles (NPs) are promising as customizable, immunostimulatory carriers to protect and deliver antigen. Although many N...

متن کامل

ژن‌های سرطان/بیضه، معرفی ژن TSGA10: مقاله مروری

Cancer/Testis antigens (CTAs) as a group of tumor antigens are the novel subjects for developing cancer vaccine and immunotherapy approaches. They aberrantly express in tumors with highest normal expression in testis, and limited or no expression in normal tissues. There are important similarities between the processes of germ-cell and cancer cell development Spermatogenesis begins at puberty w...

متن کامل

Clinical and Ultrasonographic Findings of Collagenase Induced Tendinitis in the Horse

Objective- The aim of this study was to assess the clinical and ultrasonographic alterations in the superficial digital flexor tendon (SDFT) of  horses with collagenase-induced tendinitis. Design- Experimental study.   Animals- Five clinically normal adult horse.   Procedures- Two thousand units of collagenase were injected in the center of the SDFT of forelimbs of each horse under ultrasou...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012